We use a combination of experimental and computational techniques, including microscopy, optics, nano-fabrication, spatial statistics, and image processing. We are particularly interested in super-resolution microscopy (also known as nanoscopy), which are fluorescence microscopy techniques that allow us to visualise the spatial organisation of single molecules and molecular assemblies, with the highest level of resolution and specificity. Our main biological application is in T cells, which are white blood cells that are essential for human immunity.